Journal: Frontiers in Neuroscience
Article Title: Post-ischemic reorganization of sensory responses in cerebral cortex
doi: 10.3389/fnins.2023.1151309
Figure Lengend Snippet: The top-3 independent components of the spiking response of each trial type. (A) shows each stimulation type and the corresponding independent components over the trial time. Positive coefficients are correlated with spiking activity while negative coefficients are anti-correlated with spiking activity. In the scatter plots below, each component is shown as an axis and each trial is plotted as a point within the three dimensions. Exemplar trials are highlighted and shown in insets with spike rate over time. (B) shows how the component weights (boxes) scale the component shapes to describe the features of the mean firing rate of an example channel. The corresponding blue and green arrows point to the deviations in mean firing rate while the purple arrow and line generally indicate the background firing rate that are captured by the respective component and its weight. (C) shows the reconstruction (shaded yellow) of the mean spike rate of an example channel (black line) using the descriptive weightings of the independent components.
Article Snippet: We first applied principal components analysis (PCA; MATLAB R2017a + ‘pca’ function with ‘Algorithm’ parameter set to ‘svd’) to qualitatively describe the different types of evoked responses for each condition, applying a singular value decomposition to the mean channel spike rates separately for each stimulus type; then, using the groupings for which the same basis subspace could accurately reconstruct the original observations, we seeded a reconstructed-independent components analysis algorithm (r-ICA; MATLAB R2017a + ‘rica’ function from the Statistics and Machine Learning Toolbox) using the top-3 combined-basis eigenvectors to recover a basis for the sets of components described above ( ).
Techniques: Activity Assay